S&P UPGRADES ISRAEL TO A+. Standard & Poor's upgraded Israel's long-term foreign-currency sovereign rating from A to A+ with a "Stable" outlook, citing Israel's "prosperous and resilient economy, strong institutions, ongoing fiscal consolidation, and robust external performance. The rating agency also reaffirmed Israel's local currency rating at AA-.
On September 7, 2011, the Office for Human Subject Protections (OHRP) and the Food and Drug Administration (FDA) announced in the Federal Register the availability of a joint draft document entitled, "Guidance on Exculpatory Language in Informed Consent," and are inviting public comments on that document.
Integrated CRO alliances growing but poorly executed. Results from a new CenterWatch survey show CROs generally believe that while the prevalence of integrated alliances with sponsors will grow in the next three to five years, many sponsors fall short when managing these more sophisticated relationships.
Survey: CROs increasing prices. Survey results have again surprised analysts by showing prices charged by CROs, particularly to large pharma, have increased in recent months, according to Outsourcing-Pharma.